Rameshwar N K Bamezai Selected Research

Pyruvate Kinase

1/2018	Curcumin decreases Warburg effect in cancer cells by down-regulating pyruvate kinase M2 via mTOR-HIF1α inhibition.
1/2018	Posttranslational Modifications of Pyruvate Kinase M2: Tweaks that Benefit Cancer.
1/2017	Pyruvate kinase M knockdown-induced signaling via AMP-activated protein kinase promotes mitochondrial biogenesis, autophagy, and cancer cell survival.
4/2016	WITHDRAWN: Regulation of Pyruvate Kinase M Switch towards PKM1 by LKB1-AMPK Axis Tolerates Hypoglycemic Stress in Cancer Cells.
8/2015	Moderate DNA damage promotes metabolic flux into PPP via PKM2 Y-105 phosphorylation: a feature that favours cancer cells.
8/2014	Pyruvate kinase M2 and cancer: an updated assessment.
3/2014	Missense mutations in pyruvate kinase M2 promote cancer metabolism, oxidative endurance, anchorage independence, and tumor growth in a dominant negative manner.
1/2014	Synergistic combination of gemcitabine and dietary molecule induces apoptosis in pancreatic cancer cells and down regulates PKM2 expression.
7/2013	Insulin enhances metabolic capacities of cancer cells by dual regulation of glycolytic enzyme pyruvate kinase M2.
1/2012	Resveratrol inhibits cancer cell metabolism by down regulating pyruvate kinase M2 via inhibition of mammalian target of rapamycin.

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Rameshwar N K Bamezai Research Topics

Disease

28	Neoplasms (Cancer) 11/2019 - 01/2008
8	Breast Neoplasms (Breast Cancer) 01/2015 - 01/2007
4	Carcinogenesis 11/2019 - 12/2008
3	Leprosy (Hansen's Disease) 02/2014 - 07/2010
2	Type 2 Diabetes Mellitus (MODY) 07/2018 - 01/2012
2	Pancreatic Neoplasms (Pancreatic Cancer) 05/2015 - 01/2014
2	Communicable Diseases (Infectious Diseases) 01/2014 - 02/2013
2	Bloom Syndrome 05/2010 - 05/2009
1	Neoplasm Metastasis (Metastasis) 10/2017
1	Carcinoma (Carcinomatosis) 01/2017
1	Leukemia 09/2015
1	Necrosis 02/2014
1	Infections 02/2014
1	Tuberculosis (Tuberculoses) 01/2014
1	Polyploidy 05/2010

Drug/Important Bio-Agent (IBA)

12	Pyruvate KinaseIBA 01/2018 - 05/2009
5	Protein Isoforms (Isoforms)IBA 01/2018 - 11/2010
5	EnzymesIBA 01/2017 - 05/2009
4	Glucose (Dextrose)FDA LinkGeneric 11/2019 - 01/2012
4	Mitochondrial DNA (mtDNA)IBA 11/2019 - 12/2008
4	DNA (Deoxyribonucleic Acid)IBA 08/2015 - 01/2008
4	Proteins (Proteins, Gene)FDA Link 02/2014 - 01/2009
3	Lactic Acid (Lactate)FDA LinkGeneric 11/2019 - 01/2012
3	MicroRNAs (MicroRNA)IBA 10/2017 - 04/2011
2	Transcription Factors (Transcription Factor)IBA 10/2017 - 01/2014
2	Adenosine Triphosphate (ATP)IBA 01/2017 - 09/2015
2	ResveratrolIBA 11/2015 - 01/2012
2	NADP (NADPH)IBA 08/2015 - 07/2013
2	Pharmaceutical PreparationsIBA 05/2015 - 04/2011
2	Gemcitabine FDA Link 05/2015 - 01/2014
2	IsoenzymesIBA 08/2014 - 05/2010
2	CytokinesIBA 02/2014 - 10/2011
2	Transforming Growth Factor-beta Type II ReceptorIBA 02/2014 - 10/2011
2	Messenger RNA (mRNA)IBA 04/2011 - 01/2009
2	5' Untranslated Regions (5' UTR)IBA 11/2010 - 01/2007
1	Electron Transport Complex IV (Cytochrome c Oxidase)IBA 11/2019
1	Protein Kinases (Protein Kinase)IBA 01/2018
1	CurcuminIBA 01/2018
1	AMP-Activated Protein KinasesIBA 01/2017
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2017
1	Biological ProductsIBA 10/2016
1	Hypoglycemic Agents (Hypoglycemics)IBA 04/2016
1	Chloroquine (Aralen)FDA LinkGeneric 11/2015
1	phorbolIBA 09/2015
1	Y 105 (Y-105)IBA 08/2015
1	Etoposide (VP 16)FDA LinkGeneric 08/2015
1	RNA Splicing FactorsIBA 01/2015
1	InterleukinsIBA 02/2014
1	Interleukin-6 (Interleukin 6)IBA 02/2014
1	NucleotidesIBA 01/2014
1	AcidsIBA 01/2014
1	polyacrylamideIBA 01/2014
1	PENTAIBA 01/2014
1	thymoquinoneIBA 01/2014
1	Insulin (Novolin)FDA Link 07/2013
1	Long Noncoding RNAIBA 02/2013
1	Sirtuin 1IBA 01/2012
1	Small Interfering RNA (siRNA)IBA 01/2012
1	TOR Serine-Threonine KinasesIBA 01/2012
1	Interleukin-13IBA 10/2011
1	Transforming Growth Factor-beta Type I ReceptorIBA 10/2011
1	Cisplatin (Platino)FDA LinkGeneric 04/2011
1	LuciferasesIBA 04/2011
1	Death Domain ReceptorsIBA 11/2010
1	HLA-DRB1 Chains (HLA DRB1)IBA 07/2010
1	HLA-DQA1 antigen (HLA DQA1)IBA 07/2010
1	Toll-Like Receptor 1IBA 07/2010
1	Amino Acids FDA Link 05/2009
1	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA 03/2009
1	ChromatinIBA 03/2009
1	Histones (Histone)IBA 01/2008
1	arginylprolineIBA 01/2007
1	Codon (Codons)IBA 01/2007

Therapy/Procedure

5	Therapeutics 11/2015 - 04/2011
1	Drug Therapy (Chemotherapy) 12/2008